The fourth annual WWE One Night Stand: Extreme Rules came to you on June 1 from the San Diego Sports Arena in San Diego, CA.
- Falls Count Anywhere Match: Jeff Hardy def. Umaga by pinfall in the parking lot (outside) following the Swanton Bomb from the top of a WWE Production Truck.
- #1 Contender’s 5-Way Singapore Cane Match for the ECW Title: Big Show (SmackDown) def. CM Punk (ECW), Chavo Guerrero (with Bam Neely) (ECW), Tommy Dreamer (ECW), & John Morrison (with The Miz) (ECW) by pinning Tommy Dreamer following a cane shot to the head to earn the right to face Kane for the ECW Title at Night of Champions.
- First Blood Match: John Cena def. JBL
- First Ever Divas "I Quit" Match: Beth Phoenix def. Melina
- Stretcher Match: Batista (SmackDown) def. Shawn Michaels (with Chris Jericho) (RAW)
- WWE Championship: Last Man Standing: Triple H (c) def. Randy Orton to retain.
- World Heavyweight Championship: TLC Match: The Undertaker’s Career On The Line: Edge (with La Familia) def. The Undertaker to win the vacant World Heavyweight Title and end The Undertaker’s WWE Career.
- World Heavyweight Championship
- WWE Championship
- Stretcher Match
- 5-Way Singapore Cane Match
- First Blood Match
- Falls Count Anywhere Match
- "I Quit" Match
Big Show received a gash on his head near his left eye after his head bounced off some steel steps. He received stitches post-match.
In the WWE Title Match, Randy Orton broke his collarbone.