The 510th edition of WWE SmackDown came to you from the STAPLES Center in Los Angeles, CA.
- R-Truth & The Great Khali def. Dolph Ziggler & Mike Knox by The Great Khali pinning Mike Knox following the Punjabi Plunge.
- Non-Title: Melina def. Alicia Fox (with Michelle McCool) by pin with the L.A. Splits.
- John Morrison def. Umaga by DQ after Umaga attacks John Morrison with the Samoan strap.
- Charlie Haas & Shelton Benjamin def. Cryme Tyme by Shelton Benjamin pinning Shad Gaspard following PayDirt.
- Eve def. Layla by rolling through a pinfall attempt.
- 2-on-1 Handicap Match: Edge & Chris Jericho def. Jeff Hardy by Edge pinning Jeff Hardy following the Spear.
- Edge & Chris Jericho Vs. Jeff Hardy
- John Morrison Vs. Umaga
- Charlie Haas & Shelton Benjamin Vs. Cryme Tyme
- R-Truth & The Great Khali Vs. Dolph Ziggler & Mike Knox
- Melina Vs. Alicia Fox
- Eve Vs. Layla